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Fares from Des Moines to Minneapolis
Compare live prices for DSM to MSP on Thu, 16 Apr 2026. Use the search panel to change origin, destination, passengers, cabin and trip type instantly.
DSM → MSP Approx. 373.99 km 16 Apr 2026 Live inventory
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Showing 25 of 98 live flights
Southwest Airlines
WN-2128
05:25
04/16/2026
DSM
4h 15m
1 Stop
⏱ MDW · 1h 20m
09:40
04/16/2026
MSP
₹17,231
per person
✕ Non-refundable12 fare options
Southwest Airlines
WN-2128
05:25
04/16/2026
DSM
6h 25m
1 Stop
⏱ MDW · 3h 30m
11:50
04/16/2026
MSP
₹17,231
per person
✕ Non-refundable12 fare options
Southwest Airlines
WN-2131
16:20
04/16/2026
DSM
6h 40m
1 Stop
⏱ MDW · 3h 50m
23:00
04/16/2026
MSP
₹19,114
per person
✕ Non-refundable🔥 Last 2 seats12 fare options
Delta Air Lines
DL-5020
16:23
04/16/2026
DSM
1h 16m
Non-stop
17:39
04/16/2026
MSP
₹27,812
per person
✕ Non-refundable14 fare options
Delta Air Lines
DL-5402
07:00
04/16/2026
DSM
1h 17m
Non-stop
08:17
04/16/2026
MSP
₹27,812
per person
✕ Non-refundable13 fare options
Delta Air Lines
DL-4998
10:56
04/16/2026
DSM
1h 17m
Non-stop
12:13
04/16/2026
MSP
₹27,812
per person
✕ Non-refundable14 fare options
American Airlines
AA-4121
20:03
04/16/2026
DSM
3h 56m
1 Stop
⏱ ORD · 0h 39m
23:59
04/16/2026
MSP
₹28,692
per person
✕ Non-refundable17 fare options
American Airlines
AA-4931
12:00
04/16/2026
DSM
5h 34m
1 Stop
⏱ ORD · 2h 3m
17:34
04/16/2026
MSP
₹28,692
per person
✕ Non-refundable18 fare options
American Airlines
AA-349
11:09
04/16/2026
DSM
6h 25m
1 Stop
⏱ ORD · 3h 7m
17:34
04/16/2026
MSP
₹28,692
per person
✕ Non-refundable18 fare options
United Airlines
UA-312
15:21
04/16/2026
DSM
4h 2m
1 Stop
⏱ ORD · 0h 52m
19:23
04/16/2026
MSP
₹28,692
per person
✕ Non-refundable15 fare options
United Airlines
UA-5340
06:20
04/16/2026
DSM
4h 5m
1 Stop
⏱ ORD · 0h 49m
10:25
04/16/2026
MSP
₹28,692
per person
✕ Non-refundable15 fare options
United Airlines
UA-3438
13:10
04/16/2026
DSM
4h 33m
1 Stop
⏱ ORD · 1h 19m
17:43
04/16/2026
MSP
₹28,692
per person
✕ Non-refundable14 fare options
United Airlines
UA-4782
11:25
04/16/2026
DSM
4h 43m
1 Stop
⏱ ORD · 1h 31m
16:08
04/16/2026
MSP
₹28,692
per person
✕ Non-refundable15 fare options
United Airlines
UA-3438
13:10
04/16/2026
DSM
6h 13m
1 Stop
⏱ ORD · 2h 59m
19:23
04/16/2026
MSP
₹28,692
per person
✕ Non-refundable15 fare options
United Airlines
UA-2668
08:04
04/16/2026
DSM
6h 15m
1 Stop
⏱ ORD · 3h 6m
14:19
04/16/2026
MSP
₹28,692
per person
✕ Non-refundable15 fare options
United Airlines
UA-5219
19:16
04/16/2026
DSM
4h 17m
1 Stop
⏱ ORD · 1h 5m
23:33
04/16/2026
MSP
₹28,692
per person
✕ Non-refundable🔥 Last 5 seats12 fare options
American Airlines
AA-4114
14:16
04/16/2026
DSM
6h 31m
1 Stop
⏱ ORD · 3h 2m
20:47
04/16/2026
MSP
₹28,692
per person
✕ Non-refundable13 fare options
American Airlines
AA-4203
17:01
04/16/2026
DSM
5h 20m
1 Stop
⏱ ORD · 1h 54m
22:21
04/16/2026
MSP
₹28,692
per person
✕ Non-refundable12 fare options
United Airlines
UA-312
15:21
04/16/2026
DSM
6h 39m
1 Stop
⏱ ORD · 3h 27m
22:00
04/16/2026
MSP
₹28,692
per person
✕ Non-refundable12 fare options
American Airlines
AA-1536
06:00
04/16/2026
DSM
4h 54m
1 Stop
⏱ ORD · 1h 29m
10:54
04/16/2026
MSP
₹28,726
per person
✕ Non-refundable18 fare options
United Airlines
UA-2668
08:04
04/16/2026
DSM
4h 17m
1 Stop
⏱ ORD · 1h 1m
12:21
04/16/2026
MSP
₹28,726
per person
✕ Non-refundable11 fare options
United Airlines
UA-5340
06:20
04/16/2026
DSM
6h 1m
1 Stop
⏱ ORD · 2h 41m
12:21
04/16/2026
MSP
₹28,726
per person
✕ Non-refundable🔥 Last 5 seats11 fare options
American Airlines
AA-2854
07:05
04/16/2026
DSM
5h 58m
1 Stop
⏱ CLT · 0h 48m
13:03
04/16/2026
MSP
₹28,726
per person
✕ Non-refundable18 fare options
American Airlines
AA-2854
07:05
04/16/2026
DSM
8h 1m
1 Stop
⏱ CLT · 2h 49m
15:06
04/16/2026
MSP
₹28,726
per person
✕ Non-refundable18 fare options
United Airlines
UA-1781
17:17
04/16/2026
DSM
6h 32m
1 Stop
⏱ DEN · 2h 9m
23:49
04/16/2026
MSP
₹28,726
per person
✕ Non-refundable9 fare options
😕 No flights match your filters.
Des Moines (DSM)
📍 Des Moines International Airport
🌍 United States
🕐 GMT -6
📐 Latitude: 41.534000396728516
📐 Longitude: -93.66310119628906
Minneapolis (MSP)
📍 Minneapolis-St Paul International/Wold-Chamberlain Airport
🌍 United States
🕐 GMT -6
📐 Latitude: 44.882
📐 Longitude: -93.221802

✈ Distance: Des Moines,USA to Minneapolis,USA373.99 km

📅 Results on this page are loaded for 16 Apr 2026. Click View all flights for the complete live search.

Des Moines to Minneapolis — what to expect when booking

The DSM–MSP route is served by multiple carriers throughout the year. Fares on this route can move quickly — a price available now may not be there 30 minutes later.

If your dates are flexible, try shifting your departure by a day or two using the date strip above. Mid-week departures often show lower base fares compared to weekend starts on many routes.

The distance between Des Moines,USA and Minneapolis,USA is approximately 373.99 km.

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More flights from Des Moines (DSM)
14 routes
More flights from Minneapolis (MSP)
125 routes
Minneapolis Aberdeen
MSP → ABR
Minneapolis Albany
MSP → ALB
Minneapolis Albuquerque
MSP → ABQ
Minneapolis/St. Paul Alpena
MSP → APN
Minneapolis Amsterdam
MSP → AMS
Minneapolis Anchorage
MSP → ANC
Minneapolis Appelton
MSP → ATW
Minneapolis Atlanta
MSP → ATL
Minneapolis Austin
MSP → AUS
Minneapolis Bemidji
MSP → BJI
Minneapolis/St. Paul Bentonville-Fayetteville
MSP → XNA
Minneapolis Billings
MSP → BIL
Minneapolis Birmingham
MSP → BHM
Minneapolis Bismarck
MSP → BIS
Minneapolis Bloomington
MSP → BMI
Minneapolis Boise
MSP → BOI
Minneapolis Boston
MSP → BOS
Minneapolis Bozeman
MSP → BZN
Minneapolis Brainerd
MSP → BRD
Minneapolis Buffalo
MSP → BUF
Minneapolis Calgary
MSP → YYC
Minneapolis Cancun
MSP → CUN
Minneapolis Cedar Rapids IA
MSP → CID
Minneapolis Charlotte
MSP → CLT
Minneapolis Chicago
MSP → ORD
Minneapolis Cincinnati
MSP → CVG
Minneapolis Cleveland
MSP → CLE
Minneapolis Columbus
MSP → CMH
Minneapolis Dayton
MSP → DAY
Minneapolis Denver
MSP → DEN
Minneapolis Des Moines
MSP → DSM
Minneapolis Detroit
MSP → DTW
Minneapolis/St. Paul Dickinson
MSP → DIK
Minneapolis Duluth
MSP → DLH
Minneapolis Edmonton
MSP → YEG
Minneapolis Fargo
MSP → FAR
Minneapolis Flint
MSP → FNT
Minneapolis Fort Lauderdale
MSP → FLL
Minneapolis Fort Myers
MSP → RSW
Minneapolis Fort Wayne
MSP → FWA
Minneapolis Fort Worth
MSP → DFW
Minneapolis Grand Forks
MSP → GFK
Minneapolis Grand Rapids
MSP → GRR
Minneapolis Great Falls
MSP → GTF
Minneapolis Green Bay
MSP → GRB
Minneapolis Hartford
MSP → BDL
Minneapolis Helena
MSP → HLN
Minneapolis Hibbing
MSP → HIB
Minneapolis Houston
MSP → IAH
Minneapolis Indianapolis
MSP → IND
Minneapolis International Falls
MSP → INL
Minneapolis/St. Paul Iron Mountain
MSP → IMT
Minneapolis Jacksonville
MSP → JAX
Minneapolis Kalamazoo
MSP → AZO
Minneapolis Kalispell
MSP → FCA
Minneapolis Kansas City
MSP → MCI
Minneapolis Knoxville
MSP → TYS
Minneapolis La Crosse
MSP → LSE
Minneapolis Lansing
MSP → LAN
Minneapolis Las Vegas
MSP → LAS
Minneapolis Lexington
MSP → LEX
Minneapolis Lincoln
MSP → LNK
Minneapolis London
MSP → LHR
Minneapolis Los Angeles
MSP → LAX
Minneapolis Louisville
MSP → SDF
Minneapolis Madison
MSP → MSN
Minneapolis Manchester
MSP → MHT
Minneapolis Memphis
MSP → MEM
Minneapolis Miami
MSP → MIA
Minneapolis Milwaukee
MSP → MKE
Minneapolis Minot
MSP → MOT
Minneapolis Missula
MSP → MSO
Minneapolis Moline
MSP → MLI
Minneapolis Montreal
MSP → YUL
Minneapolis Nashville
MSP → BNA
Minneapolis New Orleans
MSP → MSY
Minneapolis New York
MSP → EWR
Minneapolis Norfolk
MSP → ORF
Minneapolis Oakland
MSP → OAK
Minneapolis Oklahoma City
MSP → OKC
Minneapolis Omaha
MSP → OMA
Minneapolis Orlando
MSP → MCO
Minneapolis Palm Springs
MSP → PSP
Minneapolis Paris
MSP → CDG
Minneapolis Pasco
MSP → PSC
Minneapolis Peoria
MSP → PIA
Minneapolis Philadelphia
MSP → PHL
Minneapolis Phoenix
MSP → PHX
Minneapolis Pittsburgh International Airport
MSP → PIT
Minneapolis Portland International
MSP → PDX
Minneapolis Punta Cana
MSP → PUJ
Minneapolis Raleigh
MSP → RDU
Minneapolis Rapid City
MSP → RAP
Minneapolis Regina
MSP → YQR
Minneapolis Rhinelander
MSP → RHI
Minneapolis Richmond
MSP → RIC
Minneapolis Rochester
MSP → ROC
Minneapolis Sacramento
MSP → SMF
Minneapolis Saginaw
MSP → MBS
Minneapolis Salt Lake City
MSP → SLC
Minneapolis San Antonio
MSP → SAT
Minneapolis San Diego
MSP → SAN
Minneapolis San Francisco
MSP → SFO
Minneapolis San Jose
MSP → SJC
Minneapolis Santa Ana
MSP → SNA
Minneapolis Saskatoon
MSP → YXE
Minneapolis Seattle
MSP → SEA
Minneapolis Sioux Falls
MSP → FSD
Minneapolis South Bend
MSP → SBN
Minneapolis Spokane
MSP → GEG
Minneapolis St. Louis
MSP → STL
Minneapolis Syracuse
MSP → SYR
Minneapolis Tampa
MSP → TPA
Minneapolis Tokyo
MSP → NRT
Minneapolis Toronto
MSP → YYZ
Minneapolis Traverse City
MSP → TVC
Minneapolis Tucson
MSP → TUS
Minneapolis Tulsa
MSP → TUL
Minneapolis Vancouver
MSP → YVR
Minneapolis Washington DC
MSP → DCA
Minneapolis Watertown
MSP → ATY
Minneapolis Wausau
MSP → CWA
Minneapolis Wichita
MSP → ICT
Minneapolis/St. Paul Williston
MSP → ISN
Minneapolis Winnipeg International
MSP → YWG
❓ Frequently asked questions — Des Moines to Minneapolis flights

Generally yes — fares on most routes are most competitive around 4–6 weeks before departure. Booking earlier usually means better availability and a lower base fare when your dates are fixed.

The straight-line distance between Des Moines,USA (DSM) and Minneapolis,USA (MSP) is approximately 373.99 km. Actual flying distance may vary slightly depending on routing.

Non-stop availability on this route varies by airline schedule and season. Use the filters below to quickly check whether direct options are available on your selected date.

Mid-week departures often show lower prices than weekend travel on many routes. Use the date strip above to compare nearby days quickly.